🧪 The next big thing after GLP-1s

A breakthrough in metabolic health

Weight loss drugs like Ozempic have taken the world by storm, proving that metabolic balance is the future of health.

But what about the millions seeking a cost-effective, safer, and more sustainable solution for overindulgence, inflammation, and next-day recovery?

Enter ​SJP-001​ — a breakthrough in metabolic inflammation management from Sen-Jam.

What does it do?

You may recall Sen-Jam from our ​Deep Dive​.

SJP-001 is Sen-Jam's flagship asset, targeting inflammation caused by alcohol and excess food.

Why the time is now

Have you read ​The Innovator's Dilemma​? This world is primed for disruption.

Big Pharma laser-focused on a costly, prescription-only approach. But the next shift in metabolic health is inevitable — and it's in more accessible, safer, and cost-effective options like SJP-001.

Express interest

Sen-Jam's campaign is closing soon: Apr 7

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1. Take you to an Expression of Interest form

2. Give Sen-Jam permission to email you

To learn more about Sen-Jam without giving permission to email, ​click here​.

📰 Market Headlines

Markets plunged across the board as President Trump's latest tariff threats and political uncertainty rattled investors.

• The S&P 500 fell 1.4%, the Nasdaq plunged 2%, and the Dow dropped 1.3%.

• President Trump threatened a 200% tariff on European wines, prompting US wine shops and importers to warn of collapsing demand.

• America’s largest steel producers, Nucor ($NUE ( ▲ 2.82% ) ) and US Steel ($X ( ▲ 0.55% ) ) are up 15.7%, and 17.9% respectively, since the start of the year — outstripping the 4% decline in the S&P 500.

Big tech stocks led the decline, with Meta dropping 5%, Apple and Tesla each falling 3%, and Amazon and Alphabet both down 2.5%.

A district judge ordered thousands of federal workers to be reinstated after ruling their terminations unlawful.

MGA Entertainment accelerated plans to shift 40% of its toy manufacturing from China to India, Vietnam, and Indonesia.

🥃 Alternative investing news

Investing in Scotch whisky casks offers a unique alternative asset with strong demand and limited supply.

Unlike bottles, casks appreciate as they age. While recent market conditions have softened prices, the long-term trend is clear, particularly in emerging markets like India.

 📊 Ideas, trends, and analysis

• Initial jobless claims came in better than expected at 220,000, below the forecast of 226,000, offering a rare bright spot amid the market turmoil.

• Food inflation hit 0% in February, but dramatic price swings continue within some categories.

🧠 Make yourself heard

This week’s polls focus on international investing.

😱 Fear and Greed Index

📊 Winners and losers

Earnings

• DocuSign beat Q4 earnings estimates with revenue reaching $754.82 million; shares climbed 0.79%.

• Dollar General reported a 52% drop in net income share and announced plans to close 96 stores; shares plunged 4.82%.

• Rubrik jumped 6.11% after surpassing revenue expectations in Q4, beating estimates by $25 million.

• Ulta Beauty missed Q4 earnings expectations and cut 2025 guidance on weak consumer spending, dropping shares 3.94%.

Market movers

• Spirit Airlines emerged from bankruptcy on target this quarter after reducing $795 million in debt.

• Tesla halted Cybertruck deliveries over loose trim issues; the containment hold could extend several weeks.

• Apple planned a software update enabling AirPods to live-translate conversations, integrating the feature into iOS 19.

• The US Export-Import Bank approved a $5 billion loan for TotalEnergies’ Mozambique LNG project, reviving stalled construction.

🎤 What you said last time

"I tried Asia, it was too unpredictable for me. One word from Xi and your investment is worthless!”

📺 What to Watch Today